Sugar acids and derivatives
![Medchemexpress LLC Thiazolo[4,5-d]pyrimidine-2(3H)-thione, 7-chloro-3-(2,4-dimethoxyphenyl)-5-methyl- | 2459916-56-2 | 98.5% | 353.85 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC Thiazolo[4,5-d]pyrimidine-2(3H)-thione, 7-chloro-3-(2,4-dimethoxyphenyl)-5-methyl- | 2459916-56-2 | 98.5% | 353.85 | 25 MG
CDK1/Cyc B-IN-1 (Compound 5) is a selective CDK1/Cyc B complex inhibitor with an IC50 of 97 nM. It induces apoptosis and G2/M cell cycle arrest, and exhibits broad-spectrum cytotoxic action against various cancer cell lines.
- Selective inhibitor of the CDK1/Cyc B complex.
- Induces apoptosis and G2/M cell cycle arrest.
- Exhibits broad-spectrum cytotoxic action against cancer cell lines.
- Cytotoxic activity against HCT-116 cells and WI-38 cells.
Medchemexpress LLC 4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside | 37067-30-4 | 99.95% | 379.36 | 250 MG
4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside is a fluorogenic substrate for N-acetyl-β-D-glucosaminidase. The enzyme functionality is assessed by its ability to remove terminal β-glycosidically bound N-acetylglucosamine and N-acetylgalactosamine residues from the compound.
- Fluorogenic substrate for N-acetyl-β-D-glucosaminidase
- Assesses enzyme functionality by removing terminal β-glycosidically bound N-acetylglucosamine and N-acetylgalactosamine residues
- White to off-white solid appearance
- Classified as a fluorescent dye and enzyme labeling agent
Medchemexpress LLC 2-Propenamide, N-[2-[(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]phenyl]- | 2513289-74-0 | C15H12ClN5O | 25 MG
BSJ-04-122 is a covalent MKK4/7 dual inhibitor that inhibits MKK4 and MKK7 with IC50 values of 4 nM and 181 nM, respectively. This compound is suitable for cancer research.
- Inhibits MKK4 with an IC50 of 4 nM
- Inhibits MKK7 with an IC50 of 181 nM
- Induces robust reduction of JNK phosphorylation at concentrations of 1, 5, and 10 μM within 6 hours
- Shows enhanced antiproliferative effects when combined with JNK-IN-8
Aobchem (2-Chloro-3-methoxyphenyl)(cyclopropyl)methanol | 95% | C11H13ClO2 | 500mg
(2-Chloro-3-methoxyphenyl)(cyclopropyl)methanol | 95% | C11H13ClO2 | 500mg
eMolecules 21085-72-3 | ACETOBROMO-ALPHA-D-GLUCURONIC ACID METHYL ESTER | AstaTech | MFCD00061613 | 397.174 | C13H17BrO9 | 97.000 | COC(=O)[C@H]1O[C@H](Br)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O | 5g | 416218402
ACETOBROMO-ALPHA-D-GLUCURONIC ACID METHYL ESTER | AstaTech | 21085-72-3 | MFCD00061613 | 397.174 | C13H17BrO9 | 97.000 | COC(=O)[C@H]1O[C@H](Br)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O | 5g | 416218402
Medchemexpress LLC Octadecanoic acid, 4-methyl-2-oxo-2H-1-benzopyran-7-yl ester | 79408-85-8 | MFCD00057311 | 99.0% | 442.63 g·mol⁻¹ | C28H42O4 | 100 MG
4-Methylumbelliferyl stearate is a fluorogenic biochemical reagent used as an esterase and lipase substrate; enzymatic hydrolysis liberates fluorescent 4-methylumbelliferone for sensitive activity assays. It is supplied as a white to off-white solid with documented purity and stability for laboratory use.
- Fluorogenic substrate for esterase and lipase assays.
- Releases 4-methylumbelliferone upon enzymatic hydrolysis.
- High purity for reproducible assay performance.
- Available in multiple laboratory pack sizes to suit assay needs.
- Stable at room temperature for long-term storage; in solution store frozen for extended stability.
Medchemexpress LLC D-α-Hydroxyglutaric acid | 13095-47-1 | 98.0% | 148.11 | 25 MG
D-α-Hydroxyglutaric acid | 13095-47-1 | 98.0% | 148.11 | 25 MG
Medchemexpress LLC Achyranthoside D | 168009-91-4 | 25 MG
Achyranthoside D is a triterpene saponin isolated from the root of Achyranthes. It has a molecular formula of C53H82O25 and a molecular weight of 1119.20. This product is typically supplied as a white to off-white solid with a purity of 98.74%.
- A triterpene saponin from Achyranthes root
- White to off-white solid appearance
- Purity of 98.74%
- Molecular formula: C53H82O25
- Molecular weight: 1119.20
- Recommended storage at 4°C, protected from light
- In solvent, stable for 6 months at -80°C or 1 month at -20°C, protected from light
Medchemexpress LLC Bet-in-19 | 1643947-30-1 | 99.7% | 333.39 | C19H19N5O | 10MG
BET-IN-19 is a small-molecule BET bromodomain inhibitor provided as a high-purity research reagent for epigenetic and oncology studies. It is supplied as a powder in multiple pack sizes and displays cellular activity against AML MV4-11 cells, supporting biochemical and cell-based assays. Recommended storage: powder -20°C; in solvent -80°C (6 months) or -20°C (1 month).
- High purity (99.74%).
- Molecular formula C19H19N5O; molecular weight 333.39.
- Demonstrated inhibition of hIL-6 transcription and c-myc activity (IC50 ≤ 0.3 μM).
- Available in multiple pack sizes for flexible experimental design.
- Supplied as a powder with defined cold-storage stability.
Medchemexpress LLC Methanone, (5-methoxy-1H-indol-2-yl)phenyl- | 74588-78-6 | C16H13NO2 | 25 MG
D-64131 is an orally active tubulin inhibitor, exhibiting antimitotic activity and primarily used for cancer research. It effectively inhibits tubulin polymerization with an IC50 of 0.53 μM.
- Binds to β-tubulin, destabilizing microtubules and arresting mitotic cells in M-phase
- Inhibits proliferation of tumor cells from various organs and tissues
- Cytotoxic toward MDR/MRP tumor cell lines
- Suppresses U373 proliferation and cell cycle
- Significantly inhibits tumor growth in human amelanoic melanoma xenograft models in vivo
- Exhibits oral bioavailability and is well tolerated at efficacious doses
Medchemexpress LLC PAMP-12(human, porcine) | 196305-05-2 | 97.3% | 1618.93 | 5 MG
PAMP-12(human, porcine) is a major component of immunoreactive (ir)-PAMP, processed from the adrenomedullin precursor. It is a potent hypotensive peptide that plays a role in cardiovascular control. This peptide is specifically PAMP[9-20] with a C-terminal amide structure and has demonstrated significant dose-dependent hypotensive effects in anesthetized rats.
- Potent hypotensive peptide
- Processed from adrenomedullin precursor
- Plays a role in cardiovascular control
- PAMP[9-20] with C-terminal amide structure
- For research use only
Medchemexpress LLC Guaiacylglycerol-bet 500mg
Guaiacylglycerol-beta-guaiacyl ether is a model compound of lignin monomers that can be degraded by Bacillus amyloliquefaciens CotA[1]